During the preparation of microspheres, by adjusting the ratio of different fluorescent dyes inside the microspheres, nearly hundreds of different fluorescently encoded microspheres can be formed. Each microsphere is coated with specific protein/nucleic acid, etc. to form a capture microsphere, so as to recognize different target analytes.
Subsequently, according to the principle of flow cytometry, individual microspheres are passed through the laser detector in turn. The microspheres are identified by the classified fluorescence channel to identify the indicators; the fluorescence intensity of each parameter is obtained through the PE fluorescence channel to achieve the quantitative analysis. Finally, multiple analytes are detected simultaneously in a single reaction system.